GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs703842 | 1 | rs1599932 | chr12:58177943 | FAM119B | chr12:58166383-58176323:+ | 0.28 | 4.28 | 2.32E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs1599932 | chr12:58177943 | TSFM | chr12:58176536-58191367:+ | -0.39 | -6.83 | 3.34E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs1599932 | chr12:58177943 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.23 | -3.97 | 8.45E-5 | Multiple sclerosis |
| BLCA | cis | rs2243480 | 1 | rs160633 | chr7:65528228 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.68 | 3.93E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs160637 | chr7:65584318 | CCT6P1 | chr7:65216092-65228661:+ | 0.35 | 4.95 | 1.13E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs160639 | chr7:65579987 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.84 | 1.85E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs160642 | chr7:65558373 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.8 | 2.27E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs160644 | chr7:65558186 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.8 | 2.27E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs160646 | chr7:65556280 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.8 | 2.27E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs160648 | chr7:65543384 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.53 | 8.07E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs160652 | chr7:65538431 | CCT6P1 | chr7:65216092-65228661:+ | 0.37 | 4.93 | 1.22E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs160655 | chr7:65533214 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.51 | 8.48E-6 | Diabetic kidney disease |
| BLCA | cis | rs9815354 | 1 | rs1607908 | chr3:41905196 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.91 | 9.53E-21 | Diastolic blood pressure |
| BLCA | cis | rs881375 | 1 | rs1609810 | chr9:123642351 | LOC253039 | chr9:123605320-123616644:+ | -0.34 | -5.84 | 1.1E-8 | Rheumatoid arthritis |
| BLCA | cis | rs9815354 | 1 | rs1612124 | chr3:41967893 | ULK4 | chr3:41288091-42003660:- | -0.62 | -9.64 | 8.11E-20 | Diastolic blood pressure |